Thursday, 20th February 15th Lorne Infection and Immunity 2025

• Translating Molecular Research into Clinical Applications to Control Scabies - Katja Fischer
• Development of ex vivo models of nasal epithelia to elucidate the mechanism of Bordetella bronchispetica-mediated blockade of influenza virus replication in the nasal cavity. - Lynn Nazareth

• Establishing healthy immune-microbe interactions in human newborns - Petter Brodin
• Complex formation of ACE2 with solute carriers SLC6A19 and SLC6A20 allows for TMPRSS2 use by SARS-CoV-2 Omicron lineages - Stuart Turville
• Protein kinase C alpha modulates B cell activity in cryptosporidiosis - Chelsea Marie Braun
• Inhibition of host protein translation by enteric bacterial pathogens - Cristina Giogha
• Virus-inclusive scRNA-Seq reveals the mechanism of flavivirus neuropathogenesis  - Andrii Slonchak
• Expansion microscopy elucidates the role of Kelch 13 mutation in Plasmodium artemisinin resistance - Long K Huynh
• Legionella pneumophila manipulates mitochondrial functions - Kai Qi Yek

• In-depth single cell profiling of human CD3+ T cell response against Plasmodium falciparum and Plasmodium vivax malaria - Damian Oyong
• Functional Dynamics of Children’s T follicular helper Cells in the context of Cryptosporidiosis - Dana M Van Fossen
• High-resolution analysis of the host anti-viral immune response - Silvana Gaudieri
• A practical guide for adaptive immune receptor repertoire profiling and the characterization of antigen-induced clonotypes with applications in vaccine development, autoimmunity, and cancer - Alex Chenchik
• Impaired humoral immune memory formation after COVID-19 vaccination in patients with inflammatory bowel disease receiving anti-TNF treatment - Paul Gill
• Old dog new tricks: how point mutations change the role of IRF4 in neuroinflammation - Anne Bruestle
• To Be Advised - Dietmar Zehn

• Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050 - Benn Sartorius
• Rifaximin prophylaxis and the de novo emergence of near-pan resistant Enterococcus faecium - Glen P Carter
• Uncovering the mechanism of action of novel antimalarials from the Janssen Jumpstarter library - Madeline G. Dans
• Azithromycin analogues with improved quick-killing activity have broad mechanisms of action against malaria parasites - Emma Y Mao
• Developing precision RNA therapeutics for Tuberculosis   - Jan Schaefer
• Bacterial metabolism of dietary phenolic compounds impacts gastrointestinal microbiome community structure - Remy Young

• Antibody-dependent enhancement of inflammation during influenza virus infection - Tyron Esposito
• Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants - Shouya Feng
• Endocytosis and endosomal signaling are distinct and independent outcomes of TLR4 activation - Thomas E Schultz
• Harnessing ticks' tricks to develop therapies for inflammatory diseases - Ram Bhusal
• Mal/TIRAP in action unraveling the mechanisms of TLR signal transduction - Gabrielle C McClymont
• CRISPR activation as a tool to identify novel host viral restriction factors - Michael Beard

• Cutting through the noise: Flavivirus infection and the production of tRNA halves - Lachlan De Hayr
• Identifying novel antiviral host factors that limit influenza A virus replication - Shirley Lin
• Interrogating circulating immune cell methylome differences across the TB disease spectrum - David Vincent L Romero
• Novel vaccines that both block and deceive blood-stage malaria parasites - Alysha Literski
• Insights into the molecular recognition mechanism of a headless lipid by natural killer T cells - Praveena Thirunavukkarasu
• Investigating role of non-VAR2CSA specific antibodies in protection from placental malaria - Yvonne Dube
• Antibody-dependent serum resistance protects bacteria in chronic wound infections - Michelle N Chamoun
• Investigation of microbe associated antibody cross-reactivity in SARS-CoV-2 nucleocapsid immune response - Joshuah Fialho
• Evaluation of the effectiveness of a newly developed formaldehyde-inactivated Coxiella burnetii autogenous vaccine for the control of coxiellosis (Q fever) in dairy goats on an intensively managed coxiellosis-endemic farm in Australia - Charuni Dunuke Arachchilage
• Targeting saliva antibodies as a diagnostic test to detect different stages of small strongyle (cyathostomin) infections in equines. - Tanya King

• Identification and characterisation of natural killer cells in zebrafish - Kaushalya Perera
• Autoimmunity and molecular mimicry in COVID-19 - Magdalena Plebanski
• Exploring bacteriocin diversity in infection-causing Klebsiella isolates - Abhinaba Ray
• Anti-infective activities of antimicrobial peptides in a very preterm infant peripheral blood sepsis model - Soraya Leedham
• Investigating antimicrobial activity in the human gastrointestinal microbiome  - Jamia Hemphill
• Identifying the sources of Plasmodium falciparum infections following intensive control efforts in malaria endemic PNG - Sonakshi Madan
• Human Vd2⁺ T and MAIT cells drive the early immune response to Streptococcus pyogenes - Christopher Menne
• Elucidating the role of hnRNPM and ELAVL1 in the immune response and their regulation by viruses   - Linda Kurth
• Radioprotective 105 kDa is a positive regulator of endosomal TLR4 signalling - Carmen D Mathmann
• Defective NLRC5 signalling in macrophages leads to tumour-permissive responses promoting the development of gastric B-cell MALT lymphoma to Helicobacter infection. - Shambel A Haile

Even numbered posters will be presented during this session

• An alternative approach to identify microbial genomic features associated with inflammatory bowel disease - Sean Solari
• Characterisation of protein disulphide isomerases and their inhibitors to prevent erythrocyte invasion and egress by malaria parasites - Senna L Steen
• Helicobacter pylori induces extracellular vesicle secretion in gastric epithelial cells - Isabella Stuart
• APOBEC5 – Characterisation of a potential novel antiviral protein and marsupial homologue of placental APOBEC3. - Shuoshuo Tian
• Understanding changes in intestinal stem cell function after enteropathogenic Escherichia coli infection - Ruo Wang
• Investigating the impact of granulocyte colony-stimulating factor receptor mutations on neutrophil function using zebrafish models - Rachel S Webb
• Targets of Fc-dependent functional antibody responses in immunity to severe Plasmodium falciparum malaria in children - Grace Wright
• Matrikines are key regulators in smoke-related S. pneumoniae pulmonary infection - Xin Xu
• Outer Membrane Vesicles as Drivers of Invasive Carbapenem-Resistant Klebsiella pneumoniae Infections: Pyroptosis and Inflammatory Pathways as Key Mechanisms - Jianzhong Ye
• Unveiling Metabolic Secrets: How Polymyxin B/Zidovudine Reshapes Multidrug-Resistant Klebsiella pneumoniae - Jinxin Zhao
• Dynamics of the Nasal Microbiome in a Time of COVID: a Longitudinal Cohort Study by Enrichment Sequencing. - Marilou H Barrios
• Microchip-based sorting of high-risk material such as bacteria yeast and parasites in a disposable and fully closed cartridge system using the MACSQuant® Tyto® Sorter - Arunesh Mohandas